Enviromental and Toxigenic Virulence Factors of Salmonella typhi

Supiana Dian Nurtjahyani

FPMIPA IKIP PGRI TUBAN

Salmonella typhi is human enteric pathogen that causes a systemic disease known as typhoid fever. Some Salmonella typhi virulence factor that have been described Include, but are not limited to lipopolysaccharide (LPS) and other toxins, motility, adhesins such as fimbrae, Iron siderophores, a polysaccharide capsule (VI antigen), and various affecting Invasion. The virulence vailatlons between the various epidemic types and between ditinct serovars resulted obviously from different levels; of toxin expressions, only. These quantitative differences in toxigenicity of Salmonella correlate with particular genomic positions of the Insertion elements, Stn 'expression is modulated respect to its degree of dependency on enviromental signals such as low Iron and pH as well as micro-aerophilic conditions. The correlate enviromental and toxigenic virulence factors of Salmonella typ.ii for typhoid fever. 

Key word: enviromental, toxigenic, virulence factors, Salmonella typhi